Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

January 29, 2019

Primary Completion Date

June 29, 2021

Study Completion Date

June 29, 2021

Conditions
Pulmonary Sarcoidosis
Interventions
BIOLOGICAL

Efzofitimod 1.0 mg/kg or Placebo

Participants to receive efzofitimod 1.0 mg/kg IV every 4 weeks or placebo matched to efzofitimod every 4 weeks

BIOLOGICAL

Efzofitimod 3.0 mg/kg or Placebo

Participants to receive efzofitimod 3.0 mg/kg IV every 4 weeks or placebo matched to efzofitimod every 4 weeks

BIOLOGICAL

Efzofitimod 5.0 mg/kg or Placebo

Participants to receive efzofitimod 5.0 mg/kg IV every 4 weeks or placebo matched to efzofitimod every 4 weeks

Trial Locations (15)

22042

Inova Fairfax Medical Center, Falls Church

27858

East Carolina University, Greenville

30322

Emory University, Atlanta

33125

aTyr Investigative Site, Miami

40202

University of Louisville, Louisville

44195

Cleveland Clinic, Cleveland

45267

University of Cincinnati, Cincinnati

52242

University of Iowa, Iowa City

60611

Northwestern University, Chicago

60612

aTyr Investigative Site, Chicago

75390

UT Southwestern Medical Center, Dallas

80206

National Jewish Health, Denver

91324

aTyr Investigative Site, Northridge

92425

Medical University of South Carolina, Charleston

35294-0006

University of Alabama, Birmingham

All Listed Sponsors
collaborator

Foundation for Sarcoidosis Research

OTHER

lead

aTyr Pharma, Inc.

INDUSTRY

NCT03824392 - Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis | Biotech Hunter | Biotech Hunter