Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI

NACompletedINTERVENTIONAL
Enrollment

6,016

Participants

Timeline

Start Date

February 14, 2019

Primary Completion Date

May 7, 2022

Study Completion Date

May 6, 2023

Conditions
ST Elevation Myocardial Infarction
Interventions
DRUG

Bivalirudin

Bivaliruding 0.75 mg/kg intravenous bolus loading dose, and immediately followed by intravenous infusion of 1.75 mg/kg/h until 2-4 hours after PCI. It is recommended that ACT be monitored 5 minutes after the first administration, and if ACT is \<225 s (Hemotec method), intravenous injection of 0.35 mg/kg of bivalirudin should be administered, and the ACT re-checked to ensure it is \>225 seconds.

DRUG

unfractionated Heparin

Heparin 70 U/kg is started before coronary angiography. ACT is monitored 5 min after the first administration, and if the ACT \<225 s (Hemotec method), an intravenous injection of 1000 U of heparin is administered, and the ACT re-checked to ensure it is \>225 seconds.

Trial Locations (85)

Unknown

Bengbu Second People's Hospital, Bengbu

Fu Yang People'S Hospital, Fuyang

Linquan County Peoples Hospital, Fuyang

NO.2 People's Hospital of Fuyang City, Fuyang

Taihe County People'S Hospital, Fuyang

Bozhou Peoples Hospital, Haozhou

Huainan Oriental Hospital Group Affiliated Hospital of Anhui University of Science & Technology, Huainan

The First Hospital of Anhui University of Science&Technology, Huainan

Suzhou Municipal Hospital, Suzhou

Beijing Luhe Hospital.Capital Medical University, Beijing

Peking University Third Hospital Yanqing Hospital, Beijing

Chongqing University Fuling Hospital, Chongqing

The First Hospital of Lanzhou University, Lanzhou

Meizhou Peopie's Hospital, Meizhou

Yulin First People's Hospital, Yulin

The Affiliated Hospital of Guizhou Medical University, Guiyang

Affiliated Hospital Ofzunyi Medical University, Zunyi

Hengshuicardiovascularhospital, Hengshui

Jiaozuo People's Hospital, Jiaozuo

Kaifeng Central Hospital, Kaifeng

Luohe Central Hospital, Luohe

The First People'S Hospital of Ruzhou, Ruzhou

Shangqiu first people's Hospital, Shangqiu

The Third Affiliated Hospital Of Xinxiang Medical University, Xinxiang

Yuzhoucitypeopleshospital, Yingchuan

Fuwai Central China Cardiovascular Hospital, Zhengzhou

The First Affiliated Hospital of Zhengzhou University Center 1, Zhengzhou

The First Affiliated Hospital of Zhengzhou University Center 2, Zhengzhou

The First People'S Hospital of Xinmi, Zhengzhou

Itchoshtal Tonjinee Colere Hoatono Innehatyor Seene Ano Thohholdcy, Wuhan

Tongji Hospital Tongji Medical College of Hust, Wuhan

Wuhanasia Heart Hospital, Wuhan

Lou Di Central Hospital, Loudi

Xiangtan Central Hospital, Xiangtan

Yueyang Central Hospital, Yueyang

Chifeng College Affiliated Hospital, Chifeng

Nanjing Firsthospital, Nanjing

Jiangsutaizhou Peoples Hospital, Taizhou

Xuzhou Central Hospital, Xuzhou

First Affiliated Hospital Of Gannan Medical University, Ganzhou

Ganzhou Municipal Hospital, Ganzhou

Nan Fang Hospital.Ganzhou, Ganzhou

The Jiangxi Provincial People's Hospital, Nanchang

The Second Affiliated Hospital Of Nanchang University, Nanchang

Thefirstaffiliated Hospitalofnanchang University, Nanchang

China-Japan Union Hospital of Jilin University, Changchun

The Second Hospital of Jilin University, Changchun

Yanbian University Hospital, Yanbian

General Hospital of Benxi Iron & Steel Industry Group of Liaoning Health Industry Group, Benxi

Dalian No.3 People'S Hospital, Dalian

[email protected], Diaobingshancun

Fushun Central Hospital, Fushun

General Hospital of Fushun Mining Industry Group of Liaoning Health Industry Group, Fushun

General Hospital of Fuxin Mining Industry Group of Liaoning Health Industry Group, Fuxin

General Hospital of Northern Theater Command, Shenyang

The Fourth Affiliated Hospital of China Medical University, Shenyang

The Second Hospital of Shen Yang Medical College, Shenyang

Heze Mudan People's Hospital, Heze

Heze Municipal Hospital, Heze

Jinan Central Hospital, Jinan

Shandong Scend Provincial General Hosptial, Jinan

The Fifth People's Hospital of Jinan, Jinan

Qingdao Municipal Hospital, Qingdao

Taian City Central Hospital, Tai’an

The People's Hospital ofXin Tai City, Xintai

Zao Zhuang Central Hospital Of Shandong Guoxin Healthcare Group, Zaozhuang

Datong Third People'S Hospiatl, Datong

Shanxi Cardiovascular Hospital, Taiyuan

Department of Cardiology, Tangdu Hospital, Airforce Medical University, Xi’an

The Amliated HospitalofNorthwest University Xi'an No.3 Hospital, Xi’an

The Second Affiliated Hospital Of Xian Jiaotong University, Xi’an

Yan 'an university Affiliated Hospital, Yanan

The First Hospital of Liangshan, Xichang

The People's Hospital Of Pingchang, Bazhong City

"West China Hospital Sichuan University", Chengdu

Chengdu Second People'S Hospital, Chengdu

Hospital of Chengdu University of TCM, Chengdu

The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou

Xi Chang People'S Hospital, Xichang

Tianjin Chest Hospital, Tianjin

Tianjin Medical University General Hospital, Tianjin

The Fifth Affiliated Hospital of Xinjiang Medical University, Ürümqi

Yunnan St.John'S Hospital, Kunming

Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou

Taizhou Central Hospital, Taizhou

All Listed Sponsors
lead

Shenyang Northern Hospital

OTHER

NCT03822975 - Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI | Biotech Hunter | Biotech Hunter