Prefrontal Oscillations in Social Anxiety Disorder (POSAD)

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 12, 2019

Primary Completion Date

May 9, 2026

Study Completion Date

May 9, 2026

Conditions
Anxiety DisordersAnxietyAnxiety and Fear
Interventions
BEHAVIORAL

In vivo social exposure

Subjects will be invited to give a 5 minutes oral presentation on the topic of their choice to five examiners displaying no facial emotional reaction, after a 5 minutes period of silent waiting in front of the examiners. This waiting period is prompt to elicit anticipation-type of social anxiety.

BEHAVIORAL

Social exposure in a virtual reality setting

Subjects will give a 5 minutes oral presentation on the subject of their choice to a virtual reality panel composed of 5 examiners displaying no facial emotional reaction, after a 5 minutes period of silent waiting in front of the examiners. This waiting period is expected to elicit anticipation-type of social anxiety.

OTHER

EEG recording

EEG will be recorded with a standard 16-electrodes cap. Recordings will start before the 5 minutes waiting period and continue throughout oral presentation and recovery. The recovery period will be used as a baseline control

DIAGNOSTIC_TEST

Psychometric evaluation

"Subjects will be evaluated prior to inclusion using the following assessment tools~* Anamnestic Association for Methodology and Documentation in Psychiatry (AMDP) questionnaire~* Mini International Neuropsychiatric Interview (MINI 6.0, for psychiatric diagnoses)~* Liebowitz Social Anxiety Scale (LSAS)~* Montgomery Asberg Depression Rating Scale (MADRS)~* Brief Anxiety Scale of Tyrer (BAS)~* State-Trait Anxiety Inventory (STAI A-B)~* Global Assessment of Functioning (GAF)"

DIAGNOSTIC_TEST

Visual Analogue Scale of anxiety

"Subjects will be asked to rate their anxiety levels~* immediately before (5 minutes of silent waiting),~* during~* and after the 5-minute oral presentation (recovery)"

Trial Locations (1)

33076

RECRUITING

GENPHASS, SANPSY, CHU de Bordeaux, Bordeaux

All Listed Sponsors
lead

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV