NCT03818100 - Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 26, 2018

Primary Completion Date

April 30, 2022

Study Completion Date

December 31, 2022

Conditions

Breast Cancer

Interventions

RADIATION

Intensity modulated radiotherapy (IMRT)

Simultaneous integrated boost technique using IMRT: 48 Gray (Gy) and 40 Gy will treat tumour and breast tissue respectively, in 15 fractions over 3 weeks.

DRUG

Endocrine therapy

Endocrine therapy will commence following completion of radiotherapy, and will continue for 20 weeks.

PROCEDURE

Breast conserving surgery

Surgery carried out using local protocol following completion of endocrine therapy.

Trial Locations (1)

CB2 0QQ

RECRUITING

Cambridge University Hospitals NHS Foundation Trust, Cambridge