A Comparison of the Effects of Desflurane and TIVA on Antioxidant System in Morbidly Obese Patients

NACompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 24, 2019

Primary Completion Date

June 21, 2019

Study Completion Date

July 21, 2019

Conditions
Oxidative StressMorbid Obesity
Interventions
DIAGNOSTIC_TEST

Total Antioxidant Status

Total Antioxidant Status values will be determined using a novel automated measurement method. The colour intensity, which can be measured spectrophotometrically, is related to the total amount of oxidant molecules present in the sample. The assay is calibrated with hydrogen peroxide) and the results are expressed in terms of micromolar hydrogen peroxide equivalent per litre.

DIAGNOSTIC_TEST

Total Oxidant Status

Total Oxidant Status values will be determined using a novel automated measurement method. The colour intensity, which can be measured spectrophotometrically, is related to the total amount of oxidant molecules present in the sample. The assay is calibrated with hydrogen peroxide) and the results are expressed in terms of micromolar hydrogen peroxide equivalent per litre.

DEVICE

Bispectral Index

Bispectral Index is a method for depth of anesthesia and assessment of sedation. The values of bispectral index decreases with the deepening of anesthesia. The values of 40-60 characterize the appropriate depth of anesthesia.

OTHER

Invasive arterial monitorization

Invasive arterial monitorization will be performed to right radial artery under local anesthesia to follow up hemodynamic changes and take the blood samples.

Trial Locations (1)

44090

Sedat Akbas, Malatya

All Listed Sponsors
lead

Inonu University

OTHER

NCT03814577 - A Comparison of the Effects of Desflurane and TIVA on Antioxidant System in Morbidly Obese Patients | Biotech Hunter | Biotech Hunter