180
Participants
Start Date
March 1, 2019
Primary Completion Date
December 30, 2024
Study Completion Date
December 30, 2024
Acupuncture
The main acupoints are DU 24, EX-HN 3, DU 20, EX-HN 1, GB 12, HT 7, KI 6, GB39, and then selecting other acupoints according to TCM syndrome. The electric stimulator will be applied to DU 24, GB 12, HT 7, and LR 3 or SP 6 with a disperse-dense wave of 2/50 Hz, 0.5-1.0 mA. There are three sessions per week with each session lasting for 30 min. There will be 12 weeks of treatment for each participant in total.
Donepezil
Donepezil 5 mg will be given once daily before bed-time for 12 weeks. After the clinical trial, participants will be given conventional treatment clinically.
RECRUITING
LongHua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai
RECRUITING
Shanghai Mental Center, Shanghai Jiaotong University of Medicial School, Shanghai
RECRUITING
Huashan Hospital Fudan University, Shanghai
Shanghai Mental Health Center
OTHER
Huashan Hospital
OTHER
Shanghai University of Traditional Chinese Medicine
OTHER