60
Participants
Start Date
February 1, 2019
Primary Completion Date
May 31, 2020
Study Completion Date
June 30, 2020
Bilateral M-ECT
Following acute treatment with bilateral ECT of 6 sessions over a period of two weeks, Bilateral M-ECT will be administered at a frequency of 1 session/week for one month, then 1 session / 2 weeks for 2 months and then 1 session/month for next 3 months.
Clozapine
Clozapine will be given in accordance with Maudsley guideline: 12.5 mg on the first day, followed by 12.5mg twice daily on the second day, followed by 25mg twice daily for next two days and then increment of 25mg every two days till the target dose of 250-400 mg per day in two divided doses as per tolerability of the patients
Dept of Psychiatry, Aiims, Bhubaneswar, Bhubaneswar
All India Institute of Medical Sciences, Bhubaneswar
OTHER