Mechanisms of Pregnancy Vascular Adaptations

RecruitingOBSERVATIONAL
Enrollment

114

Participants

Timeline

Start Date

November 20, 2018

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2027

Conditions
Pre-EclampsiaVascular Diseases
Interventions
PROCEDURE

Omental Biopsy

The surgeon and clinical care team will conduct the c-section to deliver the baby and the placenta as clinically indicated. After delivery, during the closing procedures, the surgeon will indicate a time for a participating Ob/Gyn physician on the study team to collect the omental bio-specimen. Omentum is frequently excised or removed for clinical reasons during surgical procedures. Omentum has small blood vessels within it that have been used for evaluation of vascular functional changes in research. The investigators wish to isolate one to three vessels of 5 to 7 cm length. The surgeon will then close and the clinical care team will resume their standard of care activities.

Trial Locations (1)

53715

RECRUITING

UnityPoint Health-Meriter Hospital, Madison

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Wisconsin, Madison

OTHER