Modulating Pain Using Transcranial Alternating Stimulation (tACS) in Healthy Human Subjects

NACompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

April 15, 2019

Primary Completion Date

October 23, 2019

Study Completion Date

October 23, 2019

Conditions
Experimental Pain in Healthy Human Subjects
Interventions
DEVICE

10 Hz tACS of the bilateral somatosensory cortex

10 Hz tACS at 1 mA will be applied over the bilateral somatosensory cortex for 10 minutes using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber electrodes placed at electrode positions CP3 and CP4 according to the international 10-20 system.

DEVICE

10 Hz tACS of the prefrontal cortex

10 Hz tACS at 1 mA will be applied over the prefrontal cortex for 10 minutes using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber electrodes placed at electrode positions F3 and F4 according to the international 10-20 system.

DEVICE

80 Hz tACS of the bilateral somatosensory cortex

80 Hz tACS at 1 mA will be applied over the bilateral somatosensory cortex for 10 minutes using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber electrodes placed at electrode positions CP3 and CP4 according to the international 10-20 system.

DEVICE

80 Hz tACS of the prefrontal cortex

80 Hz tACS at 1 mA will be applied over the prefrontal cortex for 10 minutes using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber electrodes placed at electrode positions F3 and F4 according to the international 10-20 system.

DEVICE

Sham stimulation of the bilateral somatosensory cortex

10 Hz tACS at 1 mA will be applied over the bilateral somatosensory cortex for 10 seconds at the beginning of the experimental session using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber electrodes placed at electrode positions CP3 and CP4 according to the international 10-20 system.

DEVICE

Sham stimulation of the prefrontal cortex

10 Hz tACS at 1 mA will be applied over the prefrontal cortex for 10 seconds at the beginning of the experimental session using a Neuroconn stimulator (DC-Stimulator MR; Neuroconn, Ilmenau, Germany) and 2 5\*5 cm rubber placed at electrode positions F3 and F4 according to the international 10-20 system.

Trial Locations (1)

81675

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich

Sponsors
All Listed Sponsors
collaborator

German Research Foundation

OTHER

lead

Technical University of Munich

OTHER