Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?

NAActive, not recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 1, 2019

Primary Completion Date

July 31, 2024

Study Completion Date

December 31, 2024

Conditions
Pre Diabetes
Interventions
DIAGNOSTIC_TEST

Body Composition

Participants undergo a 5 minute body scan to determine their body composition.

DIAGNOSTIC_TEST

Maximal aerobic fitness test

Participants will complete a walking fitness text until exhaustion to determine maximal aerobic capacity.

DIAGNOSTIC_TEST

Oral glucose tolerance test

Participants will undergo an OGTT to determine insulin sensitivity.

OTHER

Muscle biopsy

Participants will give a small muscle sample pre-, immediately post and 3 hours post- the exercise trial to be assessed for lipid metabolites.

OTHER

Blood samples

Participants will give 16 blood samples, to be assessed for fatty acids in the blood.

Trial Locations (1)

L18 8EU

Liverpool John Moores University, Liverpool

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Diabetes UK

OTHER

collaborator

Liverpool University Hospitals NHS Foundation Trust

OTHER_GOV

collaborator

Royal Liverpool University Hospital

OTHER_GOV

lead

Liverpool John Moores University

OTHER

NCT03804892 - Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle? | Biotech Hunter | Biotech Hunter