Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

January 24, 2019

Primary Completion Date

January 1, 2024

Study Completion Date

February 1, 2024

Conditions
Environmental Exposure
Interventions
DRUG

[14C]-benzo[a]pyrene

Oral micro-dose (50 ng) (5.4 nCi)

DRUG

Brussels sprouts before 50 ng dose

Brussels sprouts for 7 days before 50 ng (5.4 nCi) dose of BaP

DRUG

DIM supplement before 50 ng dose

DIM supplement for 7 days before 50 ng (5.4 nCi) dose of BaP and coadministration with DIM supplement

Trial Locations (1)

97331

Oregon State University, Corvallis

All Listed Sponsors
collaborator

National Institute of Environmental Health Sciences (NIEHS)

NIH

collaborator

Lawrence Livermore National Laboratory

OTHER

collaborator

Pacific Northwest National Laboratory

FED

lead

Oregon State University

OTHER

NCT03802721 - Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet | Biotech Hunter | Biotech Hunter