Assessment of Abuse Potential of Rapastinel in Humans

PHASE1CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

November 1, 2018

Primary Completion Date

March 24, 2019

Study Completion Date

March 29, 2019

Conditions
Human Abuse Potential
Interventions
DRUG

Rapastinel

During the Treatment Phase in Part 2, participants will be administered single IV doses of rapastinel, ketamine, and placebo in a randomized crossover manner.

DRUG

Ketamine

"Part 1~Part 2, Qualification Phase:~Participants will be administered single IV doses of ketamine and placebo in a randomized crossover manner~Part 2, Treatment Phase:~Participants will be administered single IV doses of rapastinel, ketamine, and placebo in a randomized crossover manner."

DRUG

Placebo

"Part 1~Part 2, Qualification Phase:~Participants will be administered single IV doses of ketamine and placebo in a randomized crossover manner~Part 2, Treatment Phase:~Participants will be administered single IV doses of rapastinel, ketamine, and placebo in a randomized crossover manner."

Trial Locations (1)

66212

Vince and Associates Clinical Research Inc, Overland Park

All Listed Sponsors
lead

Naurex, Inc, an affiliate of Allergan plc

INDUSTRY

NCT03799900 - Assessment of Abuse Potential of Rapastinel in Humans | Biotech Hunter | Biotech Hunter