96
Participants
Start Date
May 1, 2019
Primary Completion Date
July 7, 2025
Study Completion Date
July 14, 2025
Pregnenolone
Pregnenolone 50 mg BID x 14 DAYS, followed by Pregnenolone 150 mg BID x 14 DAYS, followed by Pregnenolone 250 mg BID x thereafter for the remainder of the 8-week trial. Placebo will be identical to the pregnenolone arm, except placebo will be dispensed.
Placebo
Same as pregnenolone (active study medication), except placebo dispensed.
Durham VA Medical Center, Durham, NC, Durham
VA Office of Research and Development
FED