Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project

NACompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

November 13, 2019

Primary Completion Date

October 31, 2023

Study Completion Date

April 12, 2024

Conditions
Cocaine Use Disorder
Interventions
BEHAVIORAL

Prize-Based Contingency Management

"Participants assigned to Prize-based Contingency~Management (PBCM) conditions will receive PBCM as an adjunct to TAU. PBCM will involve twice weekly one-on-one sessions with a provider for 12-weeks. During each session, a urine specimen provided by the patient will be tested for cocaine using a point-of-care dip-test. Results of point-of-care testing will be shared with the patient and negative results will be reinforced with draws from a fish bowl containing 500 paper slips, 250 of which award small, large, or jumbo prizes (remaining slips deliver words of encouragement). Patients will be reinforced with a single prize draw for their first negative specimen; an additional prize draw will be added for each consecutive negative result (up to 8~prize draws per session). Abstinence-contingent prize draws will be reset to one upon either a positive test result or unexcused, missed appointment."

BEHAVIORAL

Treatment As Usual Outpatient Substance Use Treatment

All participants will receive treatment as usual outpatient substance use services during the 12-week treatment interval. TAU will specifically entail recommended participation in at least two outpatient group and/or individual psychotherapy encounters per week within the Center for Treatment of Addictive Disorders (CTAD) at VA Pittsburgh Healthcare System. Participants will additionally continue any previously prescribed pharmacotherapy for substance use and/or other mental health conditions, if applicable.

Trial Locations (1)

15240

VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh

All Listed Sponsors
lead

VA Office of Research and Development

FED

NCT03799341 - Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project | Biotech Hunter | Biotech Hunter