NCT03792984View on ClinicalTrials.gov

The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

December 1, 2016

Primary Completion Date

October 1, 2017

Study Completion Date

December 30, 2017

Conditions
Polycystic Ovary SyndromeVitamin D Deficiency/Insufficiency
Interventions
DIETARY_SUPPLEMENT

Vitamin D3

Vitamin D3 (Cholecalciferol) (6000 IU/daily). PO for 8 weeks.

DIETARY_SUPPLEMENT

Calcium Carbonate

Calcium carbonate (1000 mg/daily). PO for 8 weeks.

DRUG

Metformin

Metformin (1500 mg/daily; the metformin dose was increased stepwise, starting with 500 mg once daily for the 1st week, 500 mg twice daily in the 2nd week, followed by 500 mg 3 times daily from the 3rd week onward). PO for 8 weeks.

DRUG

Placebo

PO for 8 weeks.

Trial Locations (2)

Unknown

Damascus University of Obstetrics and Gynecology Hospital, Damascus

Orient Hospital, Damascus

All Listed Sponsors
lead

Damascus University

OTHER

NCT03792984 - The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients | Biotech Hunter | Biotech Hunter