Epigenetics in PostOperative Pediatric Emergence Delirium

NACompletedINTERVENTIONAL
Enrollment

175

Participants

Timeline

Start Date

September 24, 2018

Primary Completion Date

December 7, 2021

Study Completion Date

December 31, 2021

Conditions
Emergence DeliriumPostoperative ComplicationsDNA Methylation
Interventions
DRUG

Sevoflurane

All children will receive inhalation anesthesia with sevoflurane through facial mask in concentrations between 3-8% for anesthesia induction. After induction and peripheral vein puncture, the anesthesia will be maintained only with sevoflurane 3% until completion of the procedure.

DRUG

Propofol

All children will receive inhalation anesthesia with sevoflurane through facial mask in concentrations between 3-8% until lost of conscience and peripheral vein puncture. After that, sevoflurane will be turned off and its clearance will be analyzed through gas analyzer monitor. From here, anesthesia will be maintained as total venous with continuous propofol infusion 100 mcg.kg.min-1 until completion of the procedure.

Trial Locations (1)

Unknown

Instituto da Criança do Hospital das Clinicas da FMUSP, São Paulo

All Listed Sponsors
lead

University of Sao Paulo

OTHER

NCT03787849 - Epigenetics in PostOperative Pediatric Emergence Delirium | Biotech Hunter | Biotech Hunter