Effects of Hypericum Perforatum Oil on Promoting Skin Recovery in Different Human Skin Damage Models

Ointment containing Hypericum perforatum oil

Ointment containing plant oils used in Hypericum perforatum oil production and dye

60 uL of 1% w/v sodium lauryl sulphate (SLS) will be applied to skin under occlusion by large Finn chamber for 24 hours as described in the guidelines by Standardization group of European Society of Contact Dermatitis. Procedure will be performed to specified skin sites, according to randomization protocol.

Skin barrier disruption will be induced by tape-stripping. Procedure will be performed to specified skin sites, according to randomization protocol.

UV radiation will be used to induce skin erythema and damage. Procedure will be performed to specified skin sites, according to randomization protocol.

Healthy, intact skin. Procedure will be performed to specified skin sites, according to randomization protocol.