NCT03781544View on ClinicalTrials.gov

Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular Function

PHASE4RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

July 31, 2025

Study Completion Date

December 31, 2025

Conditions
Osteoarthritis of Multiple Joints of Ankle or FootHealthy
Interventions
DRUG

Tramadol

A single i.v. infusion of Tramadol (dose: 400mg/100ml) will be administered to the participants (treatment arm).

DRUG

Paracetamol

A single i.v. infusion of Paracetamol (dose: 1g/100ml) will be administered to the participants (control arm).

DRUG

Diclofenac

A single i.v. infusion of Diclofenac (dose: 75mg/100ml) will be administered to the participants (treatment arm).

Trial Locations (1)

8091

RECRUITING

University Heart Center Zurich, Zurich

All Listed Sponsors
lead

University of Zurich

OTHER