The Efficacy and Safety of Early Vitamin AD Supplementation in Very Preterm Infants

NACompletedINTERVENTIONAL
Enrollment

676

Participants

Timeline

Start Date

July 1, 2018

Primary Completion Date

June 28, 2020

Study Completion Date

June 28, 2020

Conditions
Efficacy and Safety
Interventions
OTHER

Vitamin AD

In Vitamin AD group, the very preterm infants will receive the daily vitamin AD with vitamin A at 1500 IU/day and vitamin D at 500 IU/day in drop form added to their enteral feeds when minimal feeding is introduced, and continue to 28 days or discharge. In this group ,the patient also will receive standard intravenous multivitamin preparation (1 ml/kg/d,containing VA 230 IU/kg/d, VD 80 IU/kg/d) within daily on parenteral nutrition until fed 120ml/kg.

OTHER

Control

In this group ,the patient will only receive standard intravenous multivitamin preparation (1 ml/kg/d,containing VA 230 IU/kg/d, VD 80 IU/kg/d) within daily on parenteral nutrition until fed 120ml/kg.

Trial Locations (1)

450018

Zhengzhou Children's Hospital, Zhengzhou

All Listed Sponsors
lead

Zhengzhou Children's Hospital, China

OTHER

NCT03779776 - The Efficacy and Safety of Early Vitamin AD Supplementation in Very Preterm Infants | Biotech Hunter | Biotech Hunter