NCT03778723View on ClinicalTrials.gov

Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

December 18, 2018

Primary Completion Date

December 15, 2019

Study Completion Date

January 10, 2020

Conditions
Ruptured Cerebral Aneurysm
Interventions
DRUG

Total intravenous anesthesia (TIVA)

Propofol (1.5-2 mg/kg/h) infusion, Midazolam (0.12 mg/kg/h) infusion

DRUG

Inhalation Anesthesia

Sevoflurane at a concentration of 2-2.5%

DRUG

Rescue fentanyl

Fentanyl in repeated doses (50 µg) when needed (heart rate or mean arterial blood pressure increase more than 20% of the basal value) are used for maintenance of analgesia

Trial Locations (1)

050

Sherif A Mousa, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT03778723 - Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm | Biotech Hunter | Biotech Hunter