Cryoneurolysis for the Management of Chronic Pain in Patients With Knee Osteoarthritis

A cryoprobe will be inserted percutaneously and freeze the target nerves (infrapatellar branch of the saphenous nerve \& anterior femoral cutaneous nerve) guided by ultrasound visualization.

The GLA:D program, is a standard education and exercise program for patients with osteoarthritis in Denmark. The program is performed in groups and with the supervision of an experienced physiotherapist specialized in training of musculoskeletal disorders.

The sham intervention includes a similar procedure but without freezing temperatures.