NCT03764319View on ClinicalTrials.gov

Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO

NACompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

November 6, 2018

Primary Completion Date

August 1, 2021

Study Completion Date

August 1, 2021

Conditions
ARDSAcute Lung InjuryExtracorporeal Membrane OxygenationRespiratory Distress SyndromeRespiratory Tract DiseasesLung DiseasesLung Injury, Acute
Interventions
OTHER

Ultra-protective ventilator settings

4-5 Breaths per minute; 14-16 cmH2O Positive endexpiratory pressure (PEEP) (adjust PEEP to 23 \< Plateau pressure \< 25 cmH2O); 23-25 cmH2O Plateau pressure (adjust to not exceed Tidal volume \> 4 mL/kg Predicted body weight (PBW)); \< 4mL/kg PBW Tidal volume; 1:5 Inspiration:Expiration (I:E)

OTHER

Standard ventilator settings

12-25 Breaths per minute; 8-12 cmH2O PEEP; max. 35 cmH2O Plateau pressure

Trial Locations (1)

1090

Medical University of Vienna - Division of General Anaesthesia and Intensive Care Medicine, Vienna

All Listed Sponsors
lead

Medical University of Vienna

OTHER

NCT03764319 - Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO | Biotech Hunter | Biotech Hunter