401
Participants
Start Date
April 30, 2019
Primary Completion Date
September 1, 2023
Study Completion Date
November 18, 2024
Carboplatin
Carboplatin belongs to the group of medicines known as alkylating agents. Carboplatin interferes with the growth of cancer cells, which eventually are destroyed.
Pemetrexed
Pemetrexed is a type of drug known as an anti metabolite. It stops cells making and repairing DNA so they can't grow and multiply.
Bevacizumab
Bevacizumab is an angiogenesis inhibitor. It works by targeting a protein called vascular endothelial growth factor (VEGF) that helps cancers form new blood vessels. By stopping this process, bevacizumab 'suffocates' the blood supply to the cancer, shrinking it and stopping it from growing.
Atezolizumab
Atezolizumab is in a class of medications called monoclonal antibodies. It works by blocking the action of a certain protein in cancer cells. This helps the immune system to fight against the cancer cells, and helps to slow tumor growth.
University Hospital Leuven, Leuven
CHU Liege, Liège
Unicancer - Institut Bergonie, Bordeaux
Caen- CHU, Caen
Le Mans - CHG, Le Mans
Lyon - Centre Léon Bérard, Lyon
Hospital Nord, Marseille
Curie Cancer Center Paris, Paris
Toulouse - CHU, Toulouse
Tours - CHU, Tours
SS Antonio e Biagio e Cesare Arrigo Hospital, Alessandria
IRCCS Instituto Tumori Giovanni Paolo II, Bari
Fondazione IRCCS Istituto Nazionale die Tumori, Milan
Instituto Europeo di Oncologia (IEO), Milan
AULSS2 Marca Trevigiana Treviso, Treviso
University Hospital of Turin, Turin
Alicante University Hospital ISABIAL, Alicante
ICO Hospitalet, Barcelona
Vall Hebron University Hospital/Vall Hebron Institue Oncology, Barcelona
Puerta de Hierro Hospital, Majadahonda
Hospital Parc Tauli Sabadell, Sabadell
Virgen del Rocio, Seville
Complexo Hospitalario Universitario de Vigo, Vigo
Kantonsspital Aarau, Aarau
Istituto Oncologica della Svizzera Italiana, Bellinzona
Ferdinando Cerciello, Bern
Kantonsspital Graubünden, Chur
CHUV, Lausanne
Luzerner Kantonsspital, Lucerne
Kantonsspital St. Gallen, Sankt Gallen
Kantonsspital Winterthur, Winterthur
UniversitätSpital Zürich, Zurich
Addenbrooke's Hospital, Cambridge
Clatterbridge Cancer Centre, Liverpool
Guy's and St Thomas' Hospital, London
Royal Marsden Hospital (Fulham Road), London
Royal Marsden Hospital (Sutton), London
Kent Oncology Centre, Maidstone
Wythenshawe Hospital, Manchester
Plymouth Hospitals NHS Trust, Plymouth
Weston Park Hospital, Sheffield
Royal Cornwall Hospital, Truro
Hoffmann-La Roche
INDUSTRY
ETOP IBCSG Partners Foundation
NETWORK