Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

NARecruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

May 1, 2019

Primary Completion Date

January 31, 2027

Study Completion Date

December 31, 2027

Conditions
ObesityPain, Postoperative
Interventions
DRUG

Dexmedetomidine

The intervention group will obtain the pharmacological treatment during both perioperative. Pharmacological treatment in the intervention group differs solely from the patients in the control group by replacing opioids with the following non-opioid treatment:

BEHAVIORAL

Person-centred care (PCC)

The intervention tests non-pharmacological interventions compared to conventional treatment, supplemented by an evidenced-based Person-centred care PCC approach throughout the continuum of the perioperative and until 4 weeks after discharge. This will be part of patients in Phase 2

DRUG

Esketamine

The intervention group will obtain the pharmacological treatment perioperatively. Pharmacological treatment in the intervention group differs solely from the patients in the control group by replacing opioids with the following non-opioid treatment:

DRUG

Lidocaine

The intervention group will obtain the pharmacological treatment perioperatively. Pharmacological treatment in the intervention group differs solely from the patients in the control group by replacing opioids with the following non-opioid treatment.

DEVICE

Transcutaneous Nerve Stimulation (TENS)

The intervention group will obtain non-pharmacological treatment by TENS during the entire hospital stay (both perioperative and post-operative) until discharge.

DRUG

Remifentanil

The control group receives general anesthesia with Remifentanil as the routine opioid drug during general anesthesia.

DRUG

Desflurane

The patient receives general anesthesia with Desflurane as the routine volatile anesthetic during general anesthesia

DRUG

Propofol

The patient receives general anesthesia with Propofol as the routine induction anaesthetic during general anesthesia

DRUG

Oxycodone

The control group receives Oxycodone as the routine pain management drug post-operative.

Trial Locations (2)

41678

RECRUITING

Sahlgrenska University hospital/ Östra hopsital, Gothenburg

711 82

RECRUITING

Lindesberg Hospital, Lindesberg

All Listed Sponsors
lead

Göteborg University

OTHER