Ascorbic Acid and Thiamine Effect in Septic Shock

PHASE2CompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

January 13, 2020

Study Completion Date

April 14, 2020

Conditions
Septic ShockSepsis
Interventions
DRUG

Combination therapy of vitamin C and thiamine

Vitamin C (50 mg/kg up to 3 g, every 12 hours) and thiamine (200 mg every 12 hours) intravenously administered mixed in 50 mL solution bags of normal saline for 2 days

DRUG

Normal saline solution

Normal saline solution in a volume to match the treatment components administered mixed in 50 mL solution bags of normal saline for 2 days

Trial Locations (6)

Unknown

Department of Emergency Medicine, Seoul National University Bundang Hospital,, Seongnam-si

Department of Emergency Medicine, Borame Medical Center, Seoul National University, College of Medicine, Seoul

Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine,, Seoul

Department of Emergency Medicine, Seoul National University College of Medicine,, Seoul

Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center,, Seoul

Department of Emergency Medicine, Yonsei University College of Medicine, Seoul

All Listed Sponsors
collaborator

National Research Foundation of Korea

OTHER

lead

Tae Gun Shin

OTHER

NCT03756220 - Ascorbic Acid and Thiamine Effect in Septic Shock | Biotech Hunter | Biotech Hunter