Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion

NACompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

April 2, 2018

Primary Completion Date

April 27, 2023

Study Completion Date

May 22, 2025

Conditions
Calcium Oxalate Urolithiasis
Interventions
DIETARY_SUPPLEMENT

Moderately high oxalate/low calcium diet non-colonized

Subjects will be instructed to ingest a controlled diet moderately high in oxalate before colonization

DIETARY_SUPPLEMENT

Oxalobacter formigenes

Subjects will ingest live preparation of O. formigenes

DIETARY_SUPPLEMENT

Moderately high oxalate/low calcium diet colonized

Subjects will be instructed to ingest a controlled diet moderately high in oxalate after colonization

Trial Locations (1)

35294

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

University of Alabama at Birmingham

OTHER

NCT03752684 - Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion | Biotech Hunter | Biotech Hunter