7
Participants
Start Date
January 28, 2019
Primary Completion Date
August 10, 2023
Study Completion Date
August 10, 2023
Trimethoprim
300mg of trimethoprim will be given in combination with 5mg thiamine and compared to 5mg thiamine only for both Parts 1 and 2 of the study.
Metformin
1000mg of metformin will be given in combination with 5mg thiamine and compared to 5mg thiamine only in Part 1 of the study.
Vitamin B1
5mg of thiamine will be given alone and in combination for both Parts 1 and 2 of the study.
Jean Mayer USDA Human Nutrition Research Center on Aging, Boston
Tufts University
OTHER
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
University of California, Davis
OTHER
University of California, San Francisco
OTHER