610
Participants
Start Date
June 14, 2019
Primary Completion Date
August 27, 2024
Study Completion Date
June 30, 2029
IMP Levodopa 100mg/Carbidopa 25mg
"Study treatment will comprise 3 phases:~1. Dose escalation phase: On day 1-3, patients will receive IMP solely in the morning; on day 4-6 in the morning and at lunch time;~2. full study treatment phase: from day 7 to day 34, 3 times per day (tid).~3. Treatment will stop with a tapering phase: On day 35-37, patients will receive IMP in the morning and at lunch time; on day 38 and 39 solely in the morning."
Matching placebo
"Study treatment will comprise 3 phases:~1. Dose escalation phase: On day 1-3, patients will receive Placebo solely in the morning; on day 4-6 in the morning and at lunch time;~2. full study treatment phase: from day 7 to day 34, Placebo capsules 3 times per day (tid).~3. Treatment will stop with a tapering phase: On day 35-37, patients will receive Placebo in the morning and at lunch time; on day 38 and 39 solely in the morning."
Centre hospitalier universitaire vaudois, Service de Neurologie, Lausanne
HFR Fribourg Hopital Cantonal, U. de Neurologie, Fribourg
Hôpital du Valais - Sion, Service de neurologie, Sion
Hôpital du Valais - Sion, Sion
Inselspital, Universitätsklinik für Neurologie, Bern
HFR Meyriez-Murten, Clinique de Réhabilitation, Meyriez
Felix Platter Spital, Basel
Reha Rheinfelden, Rheinfelden
Kantonsspital Aarau, Neurozentrum, Aarau
RehaClinic AG, Bad Zurzach
Kantonsspital Baden, Baden
Cereneo Schweiz AG, Vitznau
Kantonsspital Graubünden, Departement Innere Medizin / Neurologie, Chur
Rehazentrum Valens, Klinik für Neurologie und Neurorehabilitation, Valens
Klinik Lengg AG, Zurich
Head Stroke Center Klinik Hirslanden, Zurich
Universitätsspital Zürich, Klinik für Neurologie, Zurich
Kantonsspital Winterthur, Winterthur
Rehaklinik Zihlschlacht, Zihlschlacht
Kantonsspital Münsterlingen, Münsterlingen
Zürcher RehaZentrum Wald, Wald
Kantonsspital St.Gallen, Klinik für Neurologie, Sankt Gallen
Rheinburg Klinik AG, Walzenhausen
Stroke-Center Universitätsspital Basel, Basel
Swiss National Science Foundation
OTHER
University Hospital, Basel, Switzerland
OTHER