An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

October 17, 2018

Primary Completion Date

October 13, 2022

Study Completion Date

October 13, 2022

Conditions
Non-small Cell Lung Cancer (NSCLC)Head and Neck Squamous Cell Carcinoma (HNSCC)Hepatocellular Carcinoma (HCC)
Interventions
DRUG

Copanlisib

Copanlisib: lyophilisate for reconstitution and further dilution for infusion

DRUG

Nivolumab

Nivolumab: concentrate for solution for infusion

Trial Locations (6)

20903

Rhode Island Hospital, Providence

44718

Gabrail Cancer Center, Canton

80218

Rocky Mountain Cancer Centers / Denver, CO, Denver

90001

Orthopaedic Institute for Children, Los Angeles

90211-1850

Tower Hematology/Oncology Medical Group, Beverly Hills

M5G 1Z5

Princess Margaret Cancer Centre, Toronto

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY