Sleep Disruption Induced Impairments in Bone Formation

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

January 17, 2019

Primary Completion Date

March 16, 2020

Study Completion Date

March 16, 2020

Conditions
Healthy
Interventions
BEHAVIORAL

Sleep Deprivation

Participants in this arm will sleep for 8 hours at their habitual time for 1 week outpatient. Food will be provided for the outpatient week by the study. After the outpatient week participants will check into our inpatient Clinical Translational Research Center (CTRC) for a 9 day inpatient stay. During their inpatient stay participants will be sleep restricted to a 5 hour/night sleep opportunity for nights 2-7 of their inpatient stay. Outcome measures include a 24-hour serum draw (urine and blood) which will occur on night 1 (pre) and night 8 (post). Patients will be given a 10 + hour recovery sleep period on night 8 of their inpatient stay.

Trial Locations (1)

80045

Clinical & Translational Research Centers (CTRC) UCHealth, Aurora

All Listed Sponsors
collaborator

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NIH

lead

University of Colorado, Denver

OTHER

NCT03733483 - Sleep Disruption Induced Impairments in Bone Formation | Biotech Hunter | Biotech Hunter