Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis

NACompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

April 21, 2023

Study Completion Date

April 21, 2023

Conditions
Granulomatous Mastitis
Interventions
PROCEDURE

Ductal lavage

The patients received ductal lavage and breast massage every other day for two weeks. We used lidocaine (1%) for local anesthesia around the nipple. We used a lacrimal probe to identify 4-5 openings in the lactiferous ducts on the nipple and inserted the infusion cannula (21-23G). A total of 25ml of irrigation solution (5 ml of 2% lidocaine, 40 mg of triamcinolone acetonide, 20 ml of 0.9% saline and 1.0 g of ceftriaxone) was pumped into the ducts over 20-25 minutes. The patient returned to the clinic the next day for breast massage, and the cycle was repeated for two weeks.

DRUG

Corticosteroid therapy

Methylprednisolone(Common brand names: Medrol) or prednisone 20-40mg, qd for two weeks, then temper the dose gradually, and then 20mg qd for maintenance (The total duration of the treatment is 6 months).

Trial Locations (2)

510000

Jiangmen Maternal and Child Health Care Population & Family Planning Service Center, Jiangmen

524400

Lian Jiang People'S Hospital, Lianjiang

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT03724903 - Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis | Biotech Hunter | Biotech Hunter