140
Participants
Start Date
April 1, 2019
Primary Completion Date
April 21, 2023
Study Completion Date
April 21, 2023
Ductal lavage
The patients received ductal lavage and breast massage every other day for two weeks. We used lidocaine (1%) for local anesthesia around the nipple. We used a lacrimal probe to identify 4-5 openings in the lactiferous ducts on the nipple and inserted the infusion cannula (21-23G). A total of 25ml of irrigation solution (5 ml of 2% lidocaine, 40 mg of triamcinolone acetonide, 20 ml of 0.9% saline and 1.0 g of ceftriaxone) was pumped into the ducts over 20-25 minutes. The patient returned to the clinic the next day for breast massage, and the cycle was repeated for two weeks.
Corticosteroid therapy
Methylprednisolone(Common brand names: Medrol) or prednisone 20-40mg, qd for two weeks, then temper the dose gradually, and then 20mg qd for maintenance (The total duration of the treatment is 6 months).
Jiangmen Maternal and Child Health Care Population & Family Planning Service Center, Jiangmen
Lian Jiang People'S Hospital, Lianjiang
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER