Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients

NACompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

May 13, 2022

Study Completion Date

May 13, 2022

Conditions
Cough
Interventions
DRUG

Adenosine Triphosphate

Participants will inhale escalating concentrations of Adenosine Triphosphate (ATP) to induce cough and the urge-to-cough

DRUG

Capsaicin

Participants will inhale escalating concentrations of capsaicin to induce cough and the urge-to-cough

OTHER

Functional Brain Imaging

Participants will have scans of their brain activity using 3 Tesla (3T) brainstem restricted functional brain imaging (fMRI)

Trial Locations (1)

3010

The University of Melbourne, Parkville

All Listed Sponsors
collaborator

Imperial College London

OTHER

collaborator

Queen's University, Belfast

OTHER

collaborator

Monash University

OTHER

lead

Stuart Mazzone

OTHER

NCT03722849 - Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients | Biotech Hunter | Biotech Hunter