Monovalent Oral Poliovirus Vaccine Type 1 Intestinal and Humoral Immunity Study

PHASE4CompletedINTERVENTIONAL
Enrollment

1,256

Participants

Timeline

Start Date

December 18, 2018

Primary Completion Date

December 19, 2019

Study Completion Date

December 19, 2019

Conditions
Poliomyelitis
Interventions
BIOLOGICAL

mOPV1

Monovalent oral poliovirus vaccine type 1 is a type-specific, live, attenuated oral poliovirus vaccine that protects against poliovirus type 1.

BIOLOGICAL

bOPV

Bivalent oral poliovirus vaccine is a live, attenuated oral poliovirus vaccine that protects against poliovirus types 1 and 3.

BIOLOGICAL

fIPV

Fractional dose of inactivated poliovirus vaccine that protects against types 1, 2, and 3 (all polio serotypes). Given as a 0.1 milliliter (mL) dose (fractional) by intradermal injection in lieu of the full 0.5mL dose that is given intramuscularly.

Trial Locations (1)

Unknown

icddr,b study clinics (Mirpur and CTU Dhaka), Dhaka

All Listed Sponsors
collaborator

International Centre for Diarrhoeal Disease Research, Bangladesh

OTHER

lead

Centers for Disease Control and Prevention

FED

NCT03722004 - Monovalent Oral Poliovirus Vaccine Type 1 Intestinal and Humoral Immunity Study | Biotech Hunter | Biotech Hunter