The Effect of Botulinum Toxin A In Patients With Excessive Gingival Display With And Without Zinc Supplementation

PHASE3CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

January 3, 2019

Primary Completion Date

September 1, 2019

Study Completion Date

December 12, 2019

Conditions
Excessive Gingival Display
Interventions
DRUG

Botulinum toxin type A

"Botulinum toxin type A will be injected in all patients at both sides into the Yonsei point, (3Units) the point that would target 3 muscles responsible for upper lip elevation during smiling, including the LLSAN, in a single injection. This landmark was identified as the center of a triangle formed by the convergence of the LLSAN, the LLS, and the Zminor muscles and is located 1 cm lateral to the ala horizontally and 3 cm above the lip line vertically in both men and women (Hwang et al. 2009) and (Nasr et al. 2015)."

DIETARY_SUPPLEMENT

Zinc supplementation

zinc supplementation will be given to patients in the intervention arm 4 days prior to Botulinum toxin type A injection

Trial Locations (1)

11553

Faculty of Dentistry, Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER

NCT03717987 - The Effect of Botulinum Toxin A In Patients With Excessive Gingival Display With And Without Zinc Supplementation | Biotech Hunter | Biotech Hunter