DAPHNe: Paclitaxel/Trastuzumab/Pertuzumab in HER2-Positive BC

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

November 5, 2018

Primary Completion Date

October 8, 2020

Study Completion Date

September 1, 2030

Conditions
Breast Cancer
Interventions
DRUG

Paclitaxel

"Paclitaxel is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug"

DRUG

Trastuzumab

Trastuzumab works by targeting the HER2/neu receptor on cancer cells

DRUG

Pertuzumab

Pertuzumab is a monoclonal antibody which targets the surface of the cells human epidermal growth factor receptor 2 protein (HER2) on the cancer cell, interfering with HER2 causing cancer cell death

Trial Locations (5)

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

Dana-Farber Cancer Institute, Boston

01757

DF/BWCC at Milford Regional Medical Center, Milford

02190

DF/BWCC in clinical affiliation with South Shore Hospital, South Weymouth

Sponsors
All Listed Sponsors
collaborator

Susan G. Komen Breast Cancer Foundation

OTHER

collaborator

Breast Cancer Research Foundation

OTHER

collaborator

Terri Brodeur Breast Cancer Foundation

UNKNOWN

lead

Dana-Farber Cancer Institute

OTHER

NCT03716180 - DAPHNe: Paclitaxel/Trastuzumab/Pertuzumab in HER2-Positive BC | Biotech Hunter | Biotech Hunter