Prazosin for Agitation in Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

October 23, 2018

Primary Completion Date

January 5, 2022

Study Completion Date

January 5, 2022

Conditions
Alzheimer's DiseaseDisruptive Behavior
Interventions
DRUG

Prazosin

Oral prazosin HCl capsules (or placebo) will be administered twice daily, with individualized doses up to a maximum of 4 mg QAM mid-morning and 6 mg at bedtime (QHS), or matching placebo capsules

DRUG

Placebo oral capsule

Placebo capsule matched to appearance of active drug.

Trial Locations (14)

10468

VAMC: James J Peters, The Bronx

13210

SUNY Upstate Medical University, Syracuse

29401

Roper St. Francis Hospital, Charleston

40506

University of Kentucky, Lexington

78229

University of Texas, Health Science Center San Antonio, San Antonio

85351

Banner Sun Health Research Institute, Sun City

90033

University of Southern California, Los Angeles

92093

University of California, San Diego (UCSD), San Diego

93065

Alta California Medical Group, Simi Valley

94305

Stanford University, Stanford

97239

Oregon Health and Science University, Portland

98108

University of Washington, Seattle

04401

Northern Light/Acadia Hospital Eastern Maine Medical Center, Bangor

98104-2499

University of Washington, Seattle

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

collaborator

VA Puget Sound Health Care System

FED

collaborator

Alzheimer's Association

OTHER

lead

Alzheimer's Disease Cooperative Study (ADCS)

OTHER

NCT03710642 - Prazosin for Agitation in Alzheimer's Disease | Biotech Hunter | Biotech Hunter