Tranexamic Acid Plus Buccal Misoprostol on Blood Loss During and After Cesarean Delivery

NACompletedINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

November 1, 2018

Primary Completion Date

March 31, 2020

Study Completion Date

June 1, 2020

Conditions
Cesarean Section Complications
Interventions
DRUG

Oxytocin

20 IU oxytocin or placebo ampoules in 500 mL of intravenous solution infusion over 15 min after delivery of the baby.plus 2tab placebo buccal plus 110 ml saline by slow infusion

DRUG

Tranexamic acid plus misoprostol

1 gm TA or separate placebo will be diluted in 100 mL normal saline and administered slowly (over 30-60 s) intravenously by the anesthetist before skin incision,

DRUG

misoprostol

400 μg misoprostol (2 tablets of 200 μg) will be give buccally after spinal anesthesia and few minutes before skin incision;

Trial Locations (1)

81528

Aswan University, Aswān

All Listed Sponsors
lead

Aswan University Hospital

OTHER

NCT03710304 - Tranexamic Acid Plus Buccal Misoprostol on Blood Loss During and After Cesarean Delivery | Biotech Hunter | Biotech Hunter