400
Participants
Start Date
November 1, 2018
Primary Completion Date
March 31, 2020
Study Completion Date
June 1, 2020
Oxytocin
20 IU oxytocin or placebo ampoules in 500 mL of intravenous solution infusion over 15 min after delivery of the baby.plus 2tab placebo buccal plus 110 ml saline by slow infusion
Tranexamic acid plus misoprostol
1 gm TA or separate placebo will be diluted in 100 mL normal saline and administered slowly (over 30-60 s) intravenously by the anesthetist before skin incision,
misoprostol
400 μg misoprostol (2 tablets of 200 μg) will be give buccally after spinal anesthesia and few minutes before skin incision;
Aswan University, Aswān
Aswan University Hospital
OTHER