NCT03707262View on ClinicalTrials.gov

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 6, 2019

Primary Completion Date

February 28, 2025

Study Completion Date

February 28, 2025

Conditions
Renal Transplant RejectionToleranceKidney Transplant
Interventions
BIOLOGICAL

Donor CD34+ and CD3+ cells

Infusion of GCSF-mobilized, Miltenyi-enriched CD34+ hematopoietic stem/progenitor cells (HSPCs) (≥ 5 million cells/kg) and CD3+ cells (5 million cells/kg) from an HLA-identical sibling living donor, following pre-conditioning regimen of rATG and TLI.

Trial Locations (1)

90095

RECRUITING

University of California, Los Angeles, Los Angeles

All Listed Sponsors
collaborator

OneLegacy Foundation

UNKNOWN

lead

Jeffrey Veale, MD

OTHER