Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury

NACompletedINTERVENTIONAL
Enrollment

387

Participants

Timeline

Start Date

May 15, 2019

Primary Completion Date

December 15, 2021

Study Completion Date

June 15, 2022

Conditions
Postoperative Delirium
Interventions
PROCEDURE

EEG

EEG samples will be recorded before and during the cardiac surgery in order to perform spectral and coherence analyses

GENETIC

Apolipoprotein genotype

APOE genotyping will be performed for each patient

BIOLOGICAL

Serum NfL measurements

5 perioperative blood samples will be taken to measure the evolution of NfL in the serum (before and until postoperative day 5)

OTHER

Preoperative neurocognitive evaluation

Each patient will benefit from a complete neurocognitive evaluation before surgery (battery of validated cognitive tests)

Trial Locations (1)

1200

Cliniques universitaires Saint-Luc, Brussels

All Listed Sponsors
lead

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

OTHER

NCT03706989 - Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury | Biotech Hunter | Biotech Hunter