Reducing Blood Loss During Cesarean Section by Topical Versus IV Tranexamic Acid

NACompletedINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

November 1, 2018

Primary Completion Date

March 31, 2020

Study Completion Date

August 1, 2020

Conditions
Cesarean Section Complications
Interventions
OTHER

normal saline arm group

110 ml normal saline IV just before skin incision plus topical application of 120 ml normal saline applied on the placental bed during Cesarean section

DRUG

intravenous tranexamic acid

1 gm tranexamic acid (2 ampoules of Capron 500 mg /5 ml; Cairo, Egypt) intravenous just before skin incision plus110 ml normal saline IV just before skin incision plus topical application of 120 ml normal saline applied on the pelvic bed during cesarean section

DRUG

Topical tranexamic acid

2 gm topical tranexamic acid ( 4 ampoules of Capron 500 mg/5 ml applied typically) in 120 ml normal saline applied on the pelvic bed during cesarean section plus110 ml normal saline IV just before skin incision

Trial Locations (1)

81528

Aswan University, Aswān

All Listed Sponsors
lead

Aswan University Hospital

OTHER

NCT03706339 - Reducing Blood Loss During Cesarean Section by Topical Versus IV Tranexamic Acid | Biotech Hunter | Biotech Hunter