Genicular Nerve Block for Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 15, 2019

Primary Completion Date

October 16, 2019

Study Completion Date

October 22, 2019

Conditions
Post-operative Pain
Interventions
DRUG

15mL 0.25% bupivacaine

Patients will be randomly assigned to either a genicular nerve block with bupivacaine or saline

PROCEDURE

Genicular nerve block

"The ultrasound-guided genicular nerve block will be performed at the site of the superior lateral, the superior medial, and the inferior medial genicular nerves. Color Doppler will be used to identify the arterial structures which serve as landmarks for the corresponding nerves.~After skin local anesthetic infiltration, a 10 cm 21G insulated block needle will be inserted and aligned with the ultrasound scanning plane. Once satisfactory position of the needle is confirmed, 5mL of a solution containing 15 ml of 0.25% bupivacaine with 2mg dexamethasone or 5mL saline will be slowly injected. Spread of local anesthetic will be documented adjacent to the target nerve. This procedure will be performed at the site of the three genicular nerves described."

DRUG

Saline

Patients will be randomly assigned to either a genicular nerve block with bupivacaine or saline

Trial Locations (1)

27705

Duke University Hospital, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Duke University

OTHER

NCT03706313 - Genicular Nerve Block for Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter