Effect of Botulinum Toxin Type A Associated With Physical Therapy on Children With Spastic Cerebral Palsy

NACompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

May 31, 2018

Study Completion Date

June 30, 2018

Conditions
Cerebral Palsy, SpasticPhysical TherapyBotulinum Toxin
Interventions
DRUG

Botulinum toxin type A

Botulinum Toxin type A The intervention with BoNT-A (Dysport®, Ipsen Biopharmaceutical, USA) was performed in the gastrocnemius and soleus muscles, bilaterally for diplegic children and unilaterally for hemiplegic children.

OTHER

Physical Therapy

"Physiotherapeutic intervention was performed twice a week, with duration of one hour per session for 4 weeks. To maintain standardization of treatment, physiotherapists received a booklet with instructions on what treatment they should do.~The intervention protocol consisted of:~* Passive stretching of lower limbs,~* Stretching associated with the functionality of the plantar flexor muscles, knee flexors, adductors and hip flexors;~* Strengthening of the antagonist muscles with the application of BoNT-A;~* Static and dynamic balance training;~* Up and down stairs;~* Functional walking training, prioritizing the initial contact of the heel and active and passive dorsiflexion."

All Listed Sponsors
collaborator

Claudia Santos Oliveira

UNKNOWN

collaborator

Daniela Aparecida Biasotto-Gonzalez

UNKNOWN

lead

University of Nove de Julho

OTHER

NCT03704155 - Effect of Botulinum Toxin Type A Associated With Physical Therapy on Children With Spastic Cerebral Palsy | Biotech Hunter | Biotech Hunter