The Application of Zishen Yutai Pill in Aged Women Undergoing IVF-ET

NACompletedINTERVENTIONAL
Enrollment

1,467

Participants

Timeline

Start Date

March 4, 2019

Primary Completion Date

September 14, 2024

Study Completion Date

September 14, 2024

Conditions
Infertility, Female
Interventions
DRUG

Zishen Yutai Pill

Patients who undergo the long-term protocol will start taking Zishen Yutai Pill on the day of pituitary suppression, 5g three times a day (Stopping on the first 1-4 days of menstruation), and patients who undergo the antagonist protocol will start taking Zishen Yutai Pill on the 19th to 23rd day of the previous menstruation cycle, 5g three times a day (Stopping on the first 1-4 days of menstruation). The drug will be taken till 2 weeks after transplantation. If the test result is confirmed as biochemical pregnancy (HCG\>50 IU/L), patients continue to take pills till 3 weeks after the clinical pregnancy determined by the ultrasound. If it is determined that the pregnancy test is negative, stop the drug.

DRUG

Placebo

Patients who undergo the long-term protocol will start taking Placebo on the day of pituitary suppression, 5g three times a day (Stopping on the first 1-4 days of menstruation), and patients who undergo the antagonist protocol will start taking Placebo on the 19th to 23rd day of the previous menstruation cycle, 5g three times a day (Stopping on the first 1-4 days of menstruation). The drug will be taken till 2 weeks after transplantation. If the test result is confirmed as biochemical pregnancy (HCG\>50 IU/L), patients continue to take pills till 3 weeks after the clinical pregnancy determined by the ultrasound. If it is determined that the pregnancy test is negative, stop the drug.

Trial Locations (12)

410000

Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha

510000

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou

Unknown

Chongqing Health Center For Women and Children, Chongqing

The First Hospital of Lanzhou University, Lanzhou

Liuzhou Maternal and Child Healthcare Hospital, Liuzhou

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

The Third Affiliated Hospital of Zhengzhou University, Zhengzhou

The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou

Reproductive Hospital affiliated to Shandong University, Jinan

Northwest Women and Children's Hospital, Xi’an

Tangdu Hospital of Air Force Medical University, Xi’an

West China Second University Hospital/West China Women's and Children's Hospital, Sichuan

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT03703700 - The Application of Zishen Yutai Pill in Aged Women Undergoing IVF-ET | Biotech Hunter | Biotech Hunter