1,467
Participants
Start Date
March 4, 2019
Primary Completion Date
September 14, 2024
Study Completion Date
September 14, 2024
Zishen Yutai Pill
Patients who undergo the long-term protocol will start taking Zishen Yutai Pill on the day of pituitary suppression, 5g three times a day (Stopping on the first 1-4 days of menstruation), and patients who undergo the antagonist protocol will start taking Zishen Yutai Pill on the 19th to 23rd day of the previous menstruation cycle, 5g three times a day (Stopping on the first 1-4 days of menstruation). The drug will be taken till 2 weeks after transplantation. If the test result is confirmed as biochemical pregnancy (HCG\>50 IU/L), patients continue to take pills till 3 weeks after the clinical pregnancy determined by the ultrasound. If it is determined that the pregnancy test is negative, stop the drug.
Placebo
Patients who undergo the long-term protocol will start taking Placebo on the day of pituitary suppression, 5g three times a day (Stopping on the first 1-4 days of menstruation), and patients who undergo the antagonist protocol will start taking Placebo on the 19th to 23rd day of the previous menstruation cycle, 5g three times a day (Stopping on the first 1-4 days of menstruation). The drug will be taken till 2 weeks after transplantation. If the test result is confirmed as biochemical pregnancy (HCG\>50 IU/L), patients continue to take pills till 3 weeks after the clinical pregnancy determined by the ultrasound. If it is determined that the pregnancy test is negative, stop the drug.
Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou
Chongqing Health Center For Women and Children, Chongqing
The First Hospital of Lanzhou University, Lanzhou
Liuzhou Maternal and Child Healthcare Hospital, Liuzhou
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
The Third Affiliated Hospital of Zhengzhou University, Zhengzhou
The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou
Reproductive Hospital affiliated to Shandong University, Jinan
Northwest Women and Children's Hospital, Xi’an
Tangdu Hospital of Air Force Medical University, Xi’an
West China Second University Hospital/West China Women's and Children's Hospital, Sichuan
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER