Immunisation, Treatment and Controlled Human Hookworm Infection

NACompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

December 17, 2018

Primary Completion Date

September 2, 2019

Study Completion Date

September 2, 2019

Conditions
Necator Americanus Infection
Interventions
BIOLOGICAL

3x 50 L3 larvae immunisation with albendazole treatment

Immunisation with 50 Necator americanus L3 larvae at week 0, 3 and 6 with albendazole treatment at week 2, 5 and 8

OTHER

3x placebo immunisation with albendazole treatment

Mock immunisation with water at week 0, 3 and 6 with albendazole treatment at week 2, 5 and 8

BIOLOGICAL

2x 50 L3 larvae infection

After (mock) immunisation, infection with 50 Necator americanus larvae at week 13 and 15

Trial Locations (1)

2333 ZA

Leiden University Medical Center, Leiden

All Listed Sponsors
lead

Leiden University Medical Center

OTHER

NCT03702530 - Immunisation, Treatment and Controlled Human Hookworm Infection | Biotech Hunter | Biotech Hunter