Liberal Versus Restrictive Fluid Protocols in Adults

PHASE2CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 28, 2018

Primary Completion Date

June 30, 2019

Study Completion Date

June 30, 2019

Conditions
Intraoperative Complications
Interventions
DRUG

Ringer lactate

"Randomization will be done using computer generated table of random numbers in a 1:1 ratio and will be conducted using sequentially numbered, opaque and sealed envelope. The trial will be planned that neither the doctors (investigators) nor the patients will be aware of the group allocation and amount of fluid received. Intraoperative and postoperative data collections will be achieved by the same blinded anesthiologist.~Patients will be randomly allocated into two groups:~Group L: 40 patients who will be subjected to ''liberal approach of intraoperative 18-20 ml/kg/h of Ringer's lactate starting from conduction of spinal anesthesia.~Group R: 40 patients who will be subjected to ''restrictive approach of intraoperative 4-6 ml/kg/h of Ringer's lactate starting from conduction of spinal anesthesia.~Blood loss will be replaced if more than 500 ml in a ratio of 3 ml crystalloid: 1 ml blood."

Trial Locations (1)

Unknown

Assiut University Hospital, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT03697330 - Liberal Versus Restrictive Fluid Protocols in Adults | Biotech Hunter | Biotech Hunter