Acute Health Effects of Ozone Exposure

NACompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

October 7, 2018

Primary Completion Date

December 9, 2018

Study Completion Date

October 12, 2019

Conditions
Pulmonary Function
Interventions
OTHER

200 ppb ozone group

The exposure group will be exposed to 200 ppb ozone in a chamber for 2 hours while alternating 20-min rest and 10-min exercise periods. The exercise workload will be adjusted to achieve the targeted ventilation of 25 \~ 27 L/min(approximately equal to 15 \~ 18L/min/m2 body surface area). The temperature and relative humidity in the chamber will be maintained at 22±1℃ and 55%±5%, respectively.

OTHER

0 ppb ozone group

The control group will be exposed to 0 ppb ozone in a chamber for 2 hours while alternating 20-min rest and 10-min exercise periods. The exercise workload will be adjusted to achieve the targeted ventilation of 25 \~ 27 L/min(approximately equal to 15 \~ 18L/min/m2 body surface area). The temperature and relative humidity in the chamber will be maintained at 22±1℃ and 55%±5%, respectively.

Trial Locations (1)

200032

Department of Environmental Health, School of Public Health, Fudan University, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER

NCT03697174 - Acute Health Effects of Ozone Exposure | Biotech Hunter | Biotech Hunter