Colchicine for Amyotrophic Lateral Sclerosis

PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

April 10, 2019

Primary Completion Date

April 14, 2022

Study Completion Date

January 3, 2023

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG

Colchicine 1 MG Oral Tablet

Colchicine tablets depending on arm (0.01 mg/kg/day, 0.005 mg/kg/day, placebo) and on weight (\>70 kg or \<71 kg) for 30 weeks of duration.

DRUG

Colchicine 1 MG Oral Tablet

Colchicine tablets depending on arm (0.01 mg/kg/day, 0.005 mg/kg/day, placebo) and on weight (\>70 kg or \<71 kg) for 30 weeks of duration.

DRUG

Placebo Oral Tablet

Corresponding tablets for 30 weeks

Trial Locations (8)

41126

Centro Sla, Ospedale Civile S. Agostino Estense, A.O.U. Modena, Modena

Unknown

Centro Sla, University of Bari, Bari

Centro Sla, Istituto Auxologico Italiano, University of Milano, Milano, Milan

Irccs Carlo Besta, Milan

Irccs St. Raffaele Institute of Milano, Milan

Università della Campania Gianluigi Vanvitelli, Napoli

"Als Centre, C. Mondino National Neurological Institute, University of Pavia", Pavia

, Neuromuscular Omnicentre Centre, Rome, Catholic University, Rome, Roma

All Listed Sponsors
collaborator

University of Modena and Reggio Emilia

OTHER

collaborator

University of Turin, Italy

OTHER

collaborator

Istituto Auxologico Italiano

OTHER

collaborator

"IRCCS National Neurological Institute C. Mondino Foundation"

OTHER

collaborator

University of Bari

OTHER

collaborator

IRCCS San Raffaele

OTHER

collaborator

University of Padova

OTHER

collaborator

University of Milan

OTHER

collaborator

Istituto Di Ricerche Farmacologiche Mario Negri

OTHER

collaborator

University of Campania Luigi Vanvitelli

OTHER

collaborator

Catholic University of the Sacred Heart

OTHER

lead

Azienda Ospedaliero-Universitaria di Modena

OTHER

NCT03693781 - Colchicine for Amyotrophic Lateral Sclerosis | Biotech Hunter | Biotech Hunter