MRI Hippocampal Microstructure and Episodic Memory in Early Multiple Sclerosis

Expanded Disability Status Scale (EDSS), ambulation test and Multiple Sclerosis functional composite (MSFC). Medications will be recorded.

cognitive tests exploring episodic memories, information processing speed, attention/concentration and working memory.

included questionnaires for depression, anxiety, fatigue, cognitive complaint and reserve

Diffusion including NODDI, 3DT1 with and without gadolinium, 3D-FLAIR before and after gadolinium infusion, 3D White Matter nulled-MPRAGE, 3D Double-Inversion recovery sequences-weighted imaging and Resting state functional MRI