Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations

NACompletedINTERVENTIONAL
Enrollment

77

Participants

Timeline

Start Date

August 2, 2018

Primary Completion Date

January 24, 2025

Study Completion Date

July 23, 2025

Conditions
Arteriovenous Malformations, CerebralUnruptured Brain Arteriovenous MalformationRuptured Brain Arteriovenous Malformation
Interventions
PROCEDURE

Standard Trans-Arterial Embolization (TAE)

"The standard TAE, without TVE, is used in patient allocated standard treatment. The arterial approach will consist of at least one attempted catheterization for trans-arterial injection of liquid embolic.~If the operator deems, on the table, for a trans-arterial injection to be too dangerous, no arterial injection is necessary. Treatment, where indicated, can be completed through other means."

PROCEDURE

Trans-Venous Embolization (TVE)

"The experimental treatment is an attempt to completely occlude the AVM using venous catheterization and retrograde EVOH injection during the final session.~The trans-venous strategy will consist of at least one transvenous injection of ethyl vinyl alcohol (EVOH), with the choice of delivery microcatheters and other technical details left to the individual operator's discretion."

Trial Locations (9)

Unknown

University of Alberta Hospital, Edmonton

Centre hospitalier universitaire de Bordeaux, Bordeaux

Centre hospitalier régional universitaire de Brest, Brest

Centre hospitalier universitaire de Grenoble, Grenoble

Centre hospitalier universitaire Limoges, Limoges

Hôpital Forndation Adolphe de Rothschild, Paris

Centre hospitalier universitaire de Rouen Normandie, Rouen

Centre hospitalier universitaire de la Réunion, Saint-Paul

H2X 0C1

Centre Hospitalier de l'Université de Montréal, Montreal

All Listed Sponsors
lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER

NCT03691870 - Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations | Biotech Hunter | Biotech Hunter