30
Participants
Start Date
January 24, 2019
Primary Completion Date
July 1, 2020
Study Completion Date
July 1, 2021
tirofiban hydrochloride (AGGRASTAT®)
Participants will have intravenous Aggrastat administered continuously over the course of 7 days in the setting of subarachnoid hemorrhage at least 12 hours post clinically indicated Endovascular Coil Embolization procedure.
MRI
Participants will undergo 2 MRIs administered within 24 hours post Coil Embolization procedure and prior to discharge to monitor for ischemic changes.
Neurological Exam
Neurological exams will be done at screening, randomization, days 2-7, discharge, 6 week, 6 month, and one year follow up visits.
Questionnaires
Quality of Life in Brain Injury - Overall Scale (QOLIBRI-OS) and the Lawton Instrumental Activities of Daily Living (IADL) will be administered at 6 month and 1 year follow up visits.
Vital Signs
Vital signs which include temperature, respiration rate, blood pressure and O2 stats will be done at screening, randomization, days 2-7, discharge, 6 week, 6 month, and one year follow up visits.
Standard of Care Treatment
Participants will receive standard of care treatment and will not receive study drug.
University of Iowa, Iowa City
David Hasan
OTHER